Oral administration of 75 mg ACU-4429 (Acucela Inc., Seattle, WA), which produced a dose-dependent inhibition of the b-wave of electroretinograms, was well tolerated and demonstrated linear pharmacokinetics across doses, accor... more >
In patients with age-related macular degeneration (AMD), bevacizumab (Avastin, Genentech) and ranibizumab (Lucentis, Genentech) had equivalent effects on visual acuity when administered in the same dosing regimen. This was acc... more >
Low-dose Iluvien (fluocinolone acetonide, Alimera Sciences) was most effective in patients with diabetic macular edema (DME) who had the disease for 3 years or more, according to a recent analysis of the data from the 36-month... more >
The number of patients receiving coronary artery bypass graft (CABG) surgery decreased dramatically between 2001 and 2008, according to a study in the Journal of the American Medical Association.sup1/sup Researchers at the U... more >
Among postmenopausal women with prior hysterectomy, estrogen-only therapy was associated with a decreased risk of breast cancer, according to a study in the Journal of the American Medical Association.sup1/sup Andrea Z. LaCr... more >
Food addiction may be associated with similar patterns of neural activation as substance abuse, according to a study in the Archives of General Psychiatry.sup1/sup The study, conducted by Ashley N. Gearhardt, MS, MPhil, of Y... more >
High blood levels of the omega-3 docosahexaenoic acid (DHA) may be associated with an increased risk of aggressive prostate cancer, according to a study in the American Journal of Epidemiology.sup1/sup Theodore M. Brasky, PhD... more >
Babies whose mothers were exposed to organophosphate pesticides during pregnancy may have lower IQs later in childhood, according to three studies published in Environmental Health Perspectives.sup1,2,3/sup In one of the stu... more >
The Centers for Disease Control and Prevention (CDC) has reported an increase in the number of Americans diagnosed with asthma; that number grew by 4.3 million from 2001 to 2009. According to the report, nearly one in 12 peopl... more >
The US Preventive Services Task Force’s (USPSTF) 2009 guidelines, which do not recommend annual mammograms for women aged 40 to 49 years, may be negatively affecting the number of yearly screenings performed, according to tw... more >
Retinal imaging revealed an association between Alzheimer dementia and peripheral small hard drusen formation, according to a news release. Investigators captured retinal images using the Optomap (Optos Plc, Dunfermline, Sco... more >
Dosing monthly with 2 mg of VEGF Trap-Eye (aflibercept, Regeneron) resulted in a statistically significant improvement in visual acuity in patients with macular edema secondary to central retinal vein occlusion (CRVO), accordi... more >
Intravitreal delivery of angiogenesis inhibitor XV-615 (Xcovery Vision, West Palm Beach, FL) was safe and well tolerated in a 30-day rabbit study, according to research presented at ARVO.sup1/sup XV-615 is novel tyrosine kin... more >
h4ALLEN C. HO, MD/h4 strongChief Medical Editor/strong On May 1 at the Association for Research in Vision and Ophthalmology (ARVO) meeting, Daniel Martin, MD, presented the results of the Comparison of AMD Treatments Tri... more >
In August 2010, the Taliban massacred 10 medical volunteers, including six Americans, in Afghanistan. The Taliban claimed that the volunteers had tried to convert Afghans to Christianity.sup1/sup The group of doctors, nurses, ... more >
emThe Patient Protection and Affordable Care Act (PPAC Act; H.R. 3590) includes a provision for the formation of Accountable Care Organizations (ACOs). ACOs, which will comprise physicians, hospitals, and other health care pr... more >
strongFounded:/strong 1991 strongBased:/strong O’Fallon, Missouri strongNumber of Employees:/strong 359 strongOn the Web:/strong www.synergeticsusa.com strongOfficers:/strong David M. Hable, Ch... more >
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Reviewed by DAVID S. BOYER, MD
By PETER A. CAMPOCHIARO, MD
By MELISSA MURPHY; NINA NI, MD; AND CAROL L. SHIELDS, MD
By ALLEN C. HO, MD
By ROHIT ROSS LAKHANPAL, MD, FACS