Transepithelial PRK for mild to moderate myopia with or without astigmatism was safe and easier to perform than conventional PRK, according to a study in the Journal of Cataract & Refractive Surgery.1 Additionally, patients who underwent transepithelial PRK had less pain, less postoperative haze, and faster healing.
Sharbel Fahed, MD, MS, of the Lebanese American University of Beirut, and colleagues conducted a study of 100 myopic eyes with or without astigmatism. Of the 100 eyes, 50 were treated by transepithelial PRK (study group), and 50 were treated with conventional PRK, during which the epithelium was removed with alcohol. Postoperative pain, epithelial healing time, distance UCVA, manifest refraction, and haze were analyzed.
The mean subjective postoperative pain score (out of 10, with 10 indicating worst pain) at 48 hours was 2.0 in the study group and 4.5 in the control group (P=.02). The mean time to complete epithelial healing was 2.5 ±6.0 days in the study group and 3.7 ±0.8 days in the control group. At 1 week, distance UCVA was statistically significantly better in the control group; however, at 3 months, there was no statistically significant difference in distance UCVA or BCVA or manifest refraction between the two groups. Patients treated by transepithelial PRK had less postoperative haze than those treated by conventional PRK (P<.01).
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